CN103937871A - Srrp35基因和表达产物在癌症诊断与治疗中的应用 - Google Patents

Srrp35基因和表达产物在癌症诊断与治疗中的应用 Download PDF

Info

Publication number
CN103937871A
CN103937871A CN201310025221.XA CN201310025221A CN103937871A CN 103937871 A CN103937871 A CN 103937871A CN 201310025221 A CN201310025221 A CN 201310025221A CN 103937871 A CN103937871 A CN 103937871A
Authority
CN
China
Prior art keywords
srrp35
cancer
cell
albumen
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201310025221.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN103937871B (zh
Inventor
高勇
李砚东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai East Hospital
Original Assignee
Shanghai East Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai East Hospital filed Critical Shanghai East Hospital
Priority to CN201310025221.XA priority Critical patent/CN103937871B/zh
Publication of CN103937871A publication Critical patent/CN103937871A/zh
Application granted granted Critical
Publication of CN103937871B publication Critical patent/CN103937871B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
CN201310025221.XA 2013-01-23 2013-01-23 Srrp35基因和表达产物在癌症诊断与治疗中的应用 Active CN103937871B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310025221.XA CN103937871B (zh) 2013-01-23 2013-01-23 Srrp35基因和表达产物在癌症诊断与治疗中的应用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310025221.XA CN103937871B (zh) 2013-01-23 2013-01-23 Srrp35基因和表达产物在癌症诊断与治疗中的应用

Publications (2)

Publication Number Publication Date
CN103937871A true CN103937871A (zh) 2014-07-23
CN103937871B CN103937871B (zh) 2019-07-23

Family

ID=51185740

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310025221.XA Active CN103937871B (zh) 2013-01-23 2013-01-23 Srrp35基因和表达产物在癌症诊断与治疗中的应用

Country Status (1)

Country Link
CN (1) CN103937871B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105624275A (zh) * 2014-11-06 2016-06-01 上海市东方医院 Eif4g1在鳞癌诊断和治疗中的应用
CN106701902A (zh) * 2015-11-17 2017-05-24 上海市东方医院 Foxr2基因和表达产物在肝癌诊断与治疗中的应用
CN106692968A (zh) * 2015-11-16 2017-05-24 上海市东方医院 Srpk1在胃癌诊断与治疗中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2200645A1 (fr) * 2007-10-10 2010-06-30 The Trustees of Princeton University Vaccins contre le cytomégalovirus et procédés de production
EP2302036A2 (fr) * 2005-05-27 2011-03-30 Lifescan, Inc. Cellules isolés de liquide amniotique
WO2012087983A1 (fr) * 2010-12-20 2012-06-28 The General Hospital Corporation Arn non codants associés à polycomb

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2302036A2 (fr) * 2005-05-27 2011-03-30 Lifescan, Inc. Cellules isolés de liquide amniotique
EP2200645A1 (fr) * 2007-10-10 2010-06-30 The Trustees of Princeton University Vaccins contre le cytomégalovirus et procédés de production
WO2012087983A1 (fr) * 2010-12-20 2012-06-28 The General Hospital Corporation Arn non codants associés à polycomb

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Y. LI ET AL.: "SRrp35 suppresses cell proliferation and malignancy in hepatocellular carcinoma", 《HEPATOLOGY RESEARCH》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105624275A (zh) * 2014-11-06 2016-06-01 上海市东方医院 Eif4g1在鳞癌诊断和治疗中的应用
CN106692968A (zh) * 2015-11-16 2017-05-24 上海市东方医院 Srpk1在胃癌诊断与治疗中的应用
CN106701902A (zh) * 2015-11-17 2017-05-24 上海市东方医院 Foxr2基因和表达产物在肝癌诊断与治疗中的应用
CN106701902B (zh) * 2015-11-17 2020-03-20 上海市东方医院 Foxr2基因和表达产物在肝癌诊断与治疗中的应用

Also Published As

Publication number Publication date
CN103937871B (zh) 2019-07-23

Similar Documents

Publication Publication Date Title
CN105349618B (zh) 三阴性乳腺癌标记物及其在诊断和治疗中的应用
CN103937872A (zh) Crm1在胃癌诊断与治疗中的应用
CN101836116A (zh) 癌的检测方法
CN105079821A (zh) 一种长链非编码rna hnf1a-as1在制备治疗人体恶性实体瘤药物中的应用
CN106701900A (zh) 长链非编码rna herc2p3基因及其在胃癌中的用途
CN100372932C (zh) 一个细胞周期正向调控基因及其编码蛋白与应用
Xi et al. Development of Monoclonal Antibodies and Characterization of an ELISA Platform Against Kallikrein-Related Peptidase 6 as a Tumor Biomarker
CN101643511B (zh) 抑制端粒酶活性的融合蛋白、其制备及应用
CN106701902B (zh) Foxr2基因和表达产物在肝癌诊断与治疗中的应用
CN103937871A (zh) Srrp35基因和表达产物在癌症诊断与治疗中的应用
CN102634487B (zh) Gpc3单克隆抗体杂交瘤细胞株8g6及其制备方法和应用
CN108926713A (zh) 钙调磷酸酶调节蛋白1.4或其类似物在制备抑制肝癌的药物中的应用
CN103969452A (zh) 索拉菲尼个性化治疗肝癌的分型诊断试剂盒
CN102719521B (zh) 胱氨酸/谷氨酸反向转体xCT抑制剂在肝癌治疗中的应用
CN111996251B (zh) 一种恶性胶质瘤生物标志物的应用
CN106636444A (zh) Fam78a基因的用途
CN101161283B (zh) CMTM1-v17的新应用及其拮抗剂
CN106701904B (zh) Acsl4基因和表达产物在胃癌诊断与治疗中的应用
CN102181400A (zh) 杂交瘤细胞株及抗hcclm-6细胞分泌蛋白单克隆抗体
CN103083686B (zh) Dkk4基因及其编码蛋白在制备药物中的应用
CN100497625C (zh) 一种癌症基因及其医药用途
EP1905780A1 (fr) Agent d'élimination du cancer
CN113265463B (zh) Fam84b在制备食管鳞癌预后评估试剂以及在靶向治疗食管鳞癌药物的筛选中的应用
CN102808016B (zh) Arid1a基因及其编码蛋白产物的应用
CN1418223A (zh) 新的人肝癌相关蛋白及其编码序列

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant